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Candidate Genes for Late Diabetic Complications Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The new WHO criteria for classification of diabetes takes into account also clinical stages dividing the diabetic patients into noninsulin requiring (NIR), insulin requiring for control (IRC) and insu

https://www.ludc.lu.se/education-training/theses/theses-2007/eero-lindholm - 2025-10-27

Heritability of blood pressure monogenes and polygenes High blood pressure (BP) is associated with cardiovascular morbidity and mortality. Both genetic and environmental factors are implicated in BP homeostatsis and hypertension development. The aims of the present theisis were: (a) to test if ambulatory BP (ABP) is better than office BP (OBP) to capture the heritable part of BP and if BP variabil

https://www.ludc.lu.se/education-training/theses/theses-2007/cristiano-fava - 2025-10-27

From the pancreatic beta cell to the endothelium: Pathophysiological aspects of Type 2 diabetes The incidence of Diabetes Mellitus increases globally in epidemic proportions. Type 2 Diabetes is the most prevalent form of Diabetes, comprising 90% of the patients. In Type 2 Diabetes, two processes contribute to the development of the disease: insufficient insulin secretion from the pancreatic ?-cell

https://www.ludc.lu.se/education-training/theses/theses-2007/marloes-dekker-nitert - 2025-10-27

Assessment and Treatment of Impaired Insulin-Secretion and Action in Type 2 Diabetes Type 2 diabetes (T2D) is a disease characterised by varying degrees of defect in insulin secretion and insulin sensitivity and associated with increased morbidity and mortality. Optimal glycaemic control reduces the progression of diabetic complications. Over time, there is a steady deterioration of glycaemic cont

https://www.ludc.lu.se/education-training/theses/theses-2008/mozhgan-dorkhan - 2025-10-27

Adipose Tissue Gene Expression & Candidate Genes for Obesity Obesity results from an interaction between genetic and environmental factors and is a growing health problem associated with development of insulin resistance, type 2 diabetes and cardiovascular disease. This thesis has focused on investigating the genetic contribution in obesity and insulin resistance by both candidate and global gene

https://www.ludc.lu.se/education-training/theses/theses-2008/lovisa-e-johansson - 2025-10-27

Genetics of Type 2 Diabetes and Metabolic Syndrome: From Genome Wide Linkage Scans and Candidate Genes to Genome Wide Association Studies Type 2 diabetes (T2D) and metabolic syndrome (MetS) are major health problems associated with cardiovascular disease. Both diseases are influenced by a combination of genetic and environmental factors. The aim of this thesis was to identify genetic risk factors

https://www.ludc.lu.se/education-training/theses/theses-2008/marketa-sjogren - 2025-10-27

Beta-Cell Dysfunction in Huntington´s Disease Huntington's disease (HD), a fatal neurodegenerative disorder, is associated with an increased risk of diabetes mellitus. The reason for this is unknown, but considering the functional similarities of neurons and the insulin secreting pancreatic β-cell, pathological mechanisms may be shared by both cell types and account for neuronal as well as endocri

https://www.ludc.lu.se/education-training/theses/theses-2009/karl-bacos - 2025-10-27

The Impact of Ethnicity on type 2 Diabetes Type 2 diabetes mellitus is among the fastest growing diseases in the world. The reported prevalence of T2D appears to differ among various ethnic groups. Although ethnic-related differences in lifestyle factors may account for some of the predisposition to diabetes in various ethnic groups, genetic factors may play a more determinant role.High prevalence

https://www.ludc.lu.se/education-training/theses/theses-2009/forouzan-glans - 2025-10-27

Mitochondrial and Chromosomal Genomics in Type 2 Diabetes Understanding the mechanisms of complex polygenic diseases like type 2 diabetes (T2D) is as complex as their nature. Cellular processes involved in glucose homeostasis need high and reliable energy supply. Mitochondria are the major energy producers in mammalian cells. Since majority of the mitochondrial genes are encoded by the nuclear gen

https://www.ludc.lu.se/education-training/theses/theses-2009/avinash-abhyankar - 2025-10-27

Beta Cell Function: from Human Genetics to Animal Models Beta cell function is an important factor in the development of both Type 1 (T1D) and Type 2 (T2D) diabetes mellitus. T1D is characterized by a primary defect in insulin secretion due to the immune-mediated beta cell destruction, however, the more common T2D beside insulin resistance also include impaired beta cell function as a consequence

https://www.ludc.lu.se/education-training/theses/theses-2009/martins-kalis - 2025-10-27

Behörighet och dispensFör att studera vid Konsthögskolan i Malmö på masterprogrammet i fri konst med inriktning mot forskningsförberedande studier ska du ha en kandidatexamen i fri konst (Bachelor of Fine Arts) eller motsvarande. Motsvarande innebär t.ex. att du har studerat i tre år på en femårig magisterutbildning i fri konst som inte ger en kandidatexamen efter tre år. Intyg om kandidatexamen i

https://www.khm.lu.se/behorighet-och-dispens-kafps - 2025-10-27

KAFPS | 120 HP Masterprogram, forskningsförberedande studier, examensutställning 2024 Konstnärlig masterutbildning i fri konst med inriktning mot forskningsförberedande studier är ett tvåårigt utbildningsprogram på heltid. Programmets syfte är att förbereda bildkonstnärer att definiera och formulera ett forskningsprojekt i fri konst som syftar mot antagning till ett doktorandprogram i fri konst. H

https://www.khm.lu.se/utbildning-0/program-i-fri-konst/kursarkiv/masterprogram-i-fri-konst-med-inriktning-mot-forskningsforberedande-studier - 2025-10-27

KGFKO | 180 HP BFA-utställningen 2024 Det treåriga kandidatprogrammet består av eget arbete i egen ateljé, individuell handledning från professorer och andra lärare, samt schemalagda kurser inom huvudområdena teknik, gestaltning och teori. Våra internationellt verksamma professorer är aktiva inom en rad olika konstnärliga fält. Detta leder inte bara till ett viktigt utbyte inom Konsthögskolan i Ma

https://www.khm.lu.se/utbildning/program-i-fri-konst/kandidatprogram-i-fri-konst - 2025-10-27

Co-workers within Lund University Diabetes Centre have access to the Intranet. Use your LUCAT-id to log in: LUDC Intranet

https://www.ludc.lu.se/intranet - 2025-10-27

Current positionPost-doctoral fellow (MD, PhD). Surgery Research Unit, Department of Clinical Sciences, Malmö.Thesis titleSignaling and adhesive mechanisms in akute pancreatitis.List of papers includedAwal D, Abdulla A, Regnér S and Thorlacius H. TLR4 but not TLR2 regulates inflammation, and tissuew damage in acute pancreatitis induced by retrograde infrusion of taurocholate. Inflamm, Res. 2011 [E

https://www.ludc.lu.se/research-0/diabetic-complications/lab-alumni/darbaz-awla - 2025-10-27

Current positionResulatory Affairs Associate at Trial Form SupportThesis titleUterine remodeling during pregnancy; Sstudies on the effect of Heparin/Heparan SulfateList of papers includedE. Malmström, M. Sennström, A. Holmberg, H. Frielingsdorf, E. Eklund, L. Malmström, E. Tufvesson, M.F. Gomez, G. Westergren-Thorsson, Ekman-Ordeberg andA. Malmström. The importance of fibroblasts in remodelling of

https://www.ludc.lu.se/research-0/diabetic-complications/lab-alumni/anna-akerud - 2025-10-27

Current positionProject leader, Cardiology Department, Lund Universityhttp://www.med.lu.se/english/klinvetlund/cardiology/research/project_leaders/oehmanThesis titleDiabetic Vascular Complications & Inflammation Role of NFAT and TNFαList of papers includedJ.Nilsson, L M Nilsson, Y W Chen, J D Molkentn, D Erlinge & M F Gomez. High glucose activates Nuclear Factor of Activated T-cells (NFAT) in nati

https://www.ludc.lu.se/research-0/diabetic-complications/lab-alumni/jenny-ohman - 2025-10-27

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https://www.ludc.lu.se/research-0/endocrine-cell-differentiation-and-function/group-members - 2025-10-27

Team members Jens Lagerstedt, PhD, PI Claire Lyons, associate researcher Kristina Nordén, PhD, postdoc Rita Del Giudice, PhD, postdoc Shelley Edmunds, PhD, postdoc Claire Lyons,  PhD, postdoc Oktawia Nilsson-Wolanin, MSc, PhD student Raquel Lopera, student Manca Mohar, Master student   Alumni Jonathan dalla-Riva, PhD Jitka Petrlova, PhD Karin Stenkula, PhD Tatu Haataja, PhD

https://www.ludc.lu.se/research/medical-protein-science/group-members - 2025-10-27

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https://www.ludc.lu.se/research-0/medical-protein-science/group-members/raquel-lopera-student - 2025-10-27